Lidocaine, dexmedetomidine and their combination reduce isoflurane minimum alveolar concentration in dogs.
here The effects of intravenous (i.v.) lidocaine, dexmedetomidine and their combination delivered as a bolus followed by a constant rate infusion (CRI) on the minimum alveolar concentration of isoflurane (MACISO) in dogs were evaluated.Seven healthy adult dogs were included.Anaesthesia was induced with propofol and maintained with isoflurane.For ea